4-(4-Fluorophenyl)-5-(pyridin-4-yl)-1H-imidazole

Modify Date: 2026-03-03 16:43:42

4-(4-Fluorophenyl)-5-(pyridin-4-yl)-1H-imidazole Structure
4-(4-Fluorophenyl)-5-(pyridin-4-yl)-1H-imidazole structure
Common Name 4-(4-Fluorophenyl)-5-(pyridin-4-yl)-1H-imidazole
CAS Number 181630-93-3 Molecular Weight 239.25
Density N/A Boiling Point N/A
Molecular Formula C14H10FN3 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 4-(4-Fluorophenyl)-5-(pyridin-4-yl)-1H-imidazole

 Chemical & Physical Properties

Molecular Formula C14H10FN3
Molecular Weight 239.25
InChIKey MAOSUPNJVJGJEU-UHFFFAOYSA-N
SMILES C1=CC(=CC=C1C2=C(NC=N2)C3=CC=NC=C3)F

 Bioassay

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Name: In vivo inhibition of LPS-induced TNF production in mice 50 mg/Kg.
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL717406
Name: D3R2021 from Article : "Drug Design Data Resource Grand Challenge 3 Dataset: VEGFR2"
Source: BindingDB
Target: N/A
External Id: BindingDB_11026_1
Name: In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST...
Source: ChEMBL
Target: Mitogen-activated protein kinase 14
External Id: CHEMBL733334
Name: Inhibition of LPS-stimulated TNF-alpha release from human peripheral blood mononuclea...
Source: ChEMBL
Target: PBMC
External Id: CHEMBL756830
Name: In vitro inhibitory concentration against radioligand [3H]SB-202190 binding to CSBP k...
Source: ChEMBL
Target: Mitogen-activated protein kinase 11
External Id: CHEMBL653614
Name: GSK PKIS2: Screen against O. lienalis microfilariae, single point, at 3.1uM to assess...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3988182
Name: Inhibitory concentration against Prostaglandin H2 synthase 1 (PGHS-1) from ram semina...
Source: ChEMBL
Target: Prostaglandin G/H synthase 1
External Id: CHEMBL768431
Name: Inhibition of p38alpha MAP kinase
Source: ChEMBL
Target: Mitogen-activated protein kinase 14
External Id: CHEMBL1012732
Name: In vivo inhibition of ram seminal vesicle Prostaglandin G/H synthase 1 activity by de...
Source: ChEMBL
Target: Prostaglandin G/H synthase 1
External Id: CHEMBL763453
Name: Inhibitory activity against Mitogen-activated protein kinase p38 (MAP kinase)
Source: ChEMBL
Target: Mitogen-activated protein kinase 11
External Id: CHEMBL732636
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