BRD2492

Modify Date: 2025-03-26 12:09:01

BRD2492 Structure
BRD2492 structure
Common Name BRD2492
CAS Number 1821669-43-5 Molecular Weight 346.39
Density N/A Boiling Point N/A
Molecular Formula C20H18N4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BRD2492


BRD2492 is a highly potent, selective HDAC1/2 inhibitor (IC50=2/19 nM, respectively) that displays excellent selectivity versus HDAC3 (IC50=2.08 uM, ≥110-fold selectivity) and all other HDAC isoforms, increases caspase-3 activation.

 Names

Name BRD2492

 BRD2492 Biological Activity

Description BRD2492 is a highly potent, selective HDAC1/2 inhibitor (IC50=2/19 nM, respectively) that displays excellent selectivity versus HDAC3 (IC50=2.08 uM, ≥110-fold selectivity) and all other HDAC isoforms, increases caspase-3 activation.
References References 1. Wagner FF, et al. ACS Chem Biol. 2016 Feb 19;11(2):363-74. View Related Products by Target HDAC

 Chemical & Physical Properties

Molecular Formula C20H18N4O2
Molecular Weight 346.39
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