2’-Deoxy-2’-fluoro-5-methylcytidine

Modify Date: 2024-01-08 18:11:47

2’-Deoxy-2’-fluoro-5-methylcytidine Structure
2’-Deoxy-2’-fluoro-5-methylcytidine structure
Common Name 2’-Deoxy-2’-fluoro-5-methylcytidine
CAS Number 182495-80-3 Molecular Weight 259.23
Density 1.7±0.1 g/cm3 Boiling Point 495.4±55.0 °C at 760 mmHg
Molecular Formula C10H14FN3O4 Melting Point N/A
MSDS N/A Flash Point 253.4±31.5 °C

 Use of 2’-Deoxy-2’-fluoro-5-methylcytidine


2’-Deoxy-2’-fluoro-5-methylcytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

 Names

Name 2'-Deoxy-2'-fluoro-5-methylcytidine
Synonym More Synonyms

 2’-Deoxy-2’-fluoro-5-methylcytidine Biological Activity

Description 2’-Deoxy-2’-fluoro-5-methylcytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
Related Catalog
References

[1]. Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.  

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Boiling Point 495.4±55.0 °C at 760 mmHg
Molecular Formula C10H14FN3O4
Molecular Weight 259.23
Flash Point 253.4±31.5 °C
Exact Mass 259.096832
LogP -0.67
Vapour Pressure 0.0±2.9 mmHg at 25°C
Index of Refraction 1.675

 Synonyms

Cytidine, 2'-deoxy-2'-fluoro-5-methyl-
2'-Deoxy-2'-fluoro-5-methylcytidine