Tipiracil hydrochloride

Modify Date: 2025-08-23 06:03:50

Tipiracil hydrochloride Structure
Tipiracil hydrochloride structure
Common Name Tipiracil hydrochloride
CAS Number 183204-72-0 Molecular Weight 279.123
Density N/A Boiling Point N/A
Molecular Formula C9H12Cl2N4O2 Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of Tipiracil hydrochloride


Tipiracil (hydrochloride) is a thymidine phosphorylase inhibitor (TPI), used for cancer research.

 Names

Name 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1H-pyrimidine-2,4-dione,hydrochloride
Synonym More Synonyms

 Tipiracil hydrochloride Biological Activity

Description Tipiracil (hydrochloride) is a thymidine phosphorylase inhibitor (TPI), used for cancer research.
Related Catalog
In Vitro Tipiracil has antiangiogenic effect, and inhibits proliferation of endothelial cells[1]. Tipiracil is a potent inhibitor of thymidine phosphorylase, which is the enzyme that degrades FTD[2].
References

[1]. Peters GJ, et al. TAS-102: more than an antimetabolite. Lancet Oncol. 2012 Dec;13(12):e518-9.

[2]. Yoshino T, et al. TAS-102 monotherapy for pretreated metastatic colorectal cancer: a double-blind, randomised, placebo-controlled phase 2 trial. Lancet Oncol. 2012 Oct;13(10):993-1001.

 Chemical & Physical Properties

Molecular Formula C9H12Cl2N4O2
Molecular Weight 279.123
Exact Mass 278.033722
PSA 93.33000
LogP 1.95390
Storage condition 2-8°C

 Safety Information

RIDADR NONH for all modes of transport

 Synonyms

Tipiracil HCl
5-amino-1-[(5-chloro-2,6-dihydroxypyrimidin-4-yl)methyl]-3,4-dihydro-2H-pyrrolium chloride
2,4(1H,3H)-Pyrimidinedione, 5-chloro-6-[(2-imino-1-pyrrolidinyl)methyl]-, hydrochloride (1:1)
TAS-1-462
Tipiracil hydrochloride
2H-pyrrolium, 5-amino-1-[(5-chloro-2,6-dihydroxy-4-pyrimidinyl)methyl]-3,4-dihydro-, chloride (1:1)
5-Chloro-6-[(2-imino-1-pyrrolidinyl)methyl]-2,4(1H,3H)-pyrimidinedione hydrochloride (1:1)
Tipiracil hydrochloride (JAN)
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here





Get all suppliers and price by the below link:

Tipiracil hydrochloride suppliers


Price: $66/10mM*1mLinWater

Reference only. check more Tipiracil hydrochloride price