(Pyr3)-Amyloid β-Protein (3-42) ammonium salt

Modify Date: 2024-01-14 09:54:18

(Pyr3)-Amyloid β-Protein (3-42) ammonium salt Structure
(Pyr3)-Amyloid β-Protein (3-42) ammonium salt structure
Common Name (Pyr3)-Amyloid β-Protein (3-42) ammonium salt
CAS Number 183449-57-2 Molecular Weight 4309.86
Density N/A Boiling Point N/A
Molecular Formula C196H299N53O55S Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of (Pyr3)-Amyloid β-Protein (3-42) ammonium salt


(Pyr3)-Amyloid β-Protein (3-42) is the predominant amyloid β-peptide structure deposited in human brain of Alzheimer's disease and Down's syndrome patients. (Pyr3)-Amyloid β-Protein (3-42) is suggested to accumulate in the brain and to trigger the formation of insoluble amyloid β-peptide deposits[1].

 Names

Name [pGlu3]-Amyloid β-Protein Fragment 3-42
Synonym More Synonyms

  Biological Activity

Description (Pyr3)-Amyloid β-Protein (3-42) is the predominant amyloid β-peptide structure deposited in human brain of Alzheimer's disease and Down's syndrome patients. (Pyr3)-Amyloid β-Protein (3-42) is suggested to accumulate in the brain and to trigger the formation of insoluble amyloid β-peptide deposits[1].
Related Catalog
References

[1]. Takahashi-Ito K, et.al. Memantine inhibits β-amyloid aggregation and disassembles preformed β-amyloid aggregates. Biochem Biophys Res Commun. 2017 Nov 4;493(1):158-163.  

 Chemical & Physical Properties

Molecular Formula C196H299N53O55S
Molecular Weight 4309.86
Exact Mass 4307.19000
PSA 1722.65000
LogP 5.49010
Appearance of Characters solid
Storage condition −20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3

 Synonyms

pyr-phe-arg-his-asp-ser-gly-tyr-glu-val-his-his-gln-lys-leu-val-phe-phe-ala-glu-asp-val-gly-ser-asn-lys-gly-ala-ile-ile-gly-leu-met-val-gly-gly-val-val-ile-ala trifluoroacetate
MFCD03457978
Pyr-FRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA