EGFR-IN-87

Modify Date: 2025-08-25 12:10:44

EGFR-IN-87 Structure
EGFR-IN-87 structure
Common Name EGFR-IN-87
CAS Number 1835666-87-9 Molecular Weight 499.61
Density N/A Boiling Point N/A
Molecular Formula C28H33N7O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of EGFR-IN-87


EGFR-IN-87 is a EGFR tyrosine kinase inhibitor. EGFR-IN-87 has IC50 value of 3.1 nM, 1.3 nM and 7.1 nM for EGFR_d746-750, EGFR_L858R/T790 and EGFR_WT in A431 cells, respectively. EGFR-IN-87 can be used for cancer diseases research[1].

 Names

Name EGFR-IN-87

 EGFR-IN-87 Biological Activity

Description EGFR-IN-87 is a EGFR tyrosine kinase inhibitor. EGFR-IN-87 has IC50 value of 3.1 nM, 1.3 nM and 7.1 nM for EGFR_d746-750, EGFR_L858R/T790 and EGFR_WT in A431 cells, respectively. EGFR-IN-87 can be used for cancer diseases research[1].
Related Catalog
Target

EGFR tyrosine kinase inhibitor for treatment of cancer, IC50 for EGFR d746~750, EGFR L858R/T790, EGFR WT was in nanomolar level.;WO2017120429(Example 2);陈婷婷要求上线,2023/9/15

References

[1]. Song Y.T, et al. Selective inhibitors of clinically important mutants of the egfr tyrosine kinase. The United States, WO2017120429 A1. 2017-07-13.

 Chemical & Physical Properties

Molecular Formula C28H33N7O2
Molecular Weight 499.61
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