leucomycin A6

Modify Date: 2024-01-30 15:48:40

leucomycin A6 Structure
leucomycin A6 structure
Common Name leucomycin A6
CAS Number 18361-48-3 Molecular Weight 799.94200
Density 1.22g/cm3 Boiling Point 867ºC at 760mmHg
Molecular Formula C40H65NO15 Melting Point N/A
MSDS N/A Flash Point 478.1ºC

 Names

Name [6-[6-[[(11Z,13E)-4-acetyloxy-10-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy]-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy-4-hydroxy-2,4-dimethyloxan-3-yl] propanoate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.22g/cm3
Boiling Point 867ºC at 760mmHg
Molecular Formula C40H65NO15
Molecular Weight 799.94200
Flash Point 478.1ºC
Exact Mass 799.43500
PSA 206.05000
LogP 2.37730
Vapour Pressure 4.52E-35mmHg at 25°C
Index of Refraction 1.537

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OH4725500
CHEMICAL NAME :
Leucomycin A6
CAS REGISTRY NUMBER :
18361-48-3
LAST UPDATED :
199512
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C40-H65-N-O15
MOLECULAR WEIGHT :
800.06
WISWESSER LINE NOTATION :
T-16-OV KU MUTJ DOO2 EO1 G1VH I1 JQ P1 FO- BT6OTJ CQ DN1&1 F1 EO- FT6OTJ B1 COV2 DQ D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
9600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,810,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4900 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JJANAX Japanese Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan) V.21- 1968- Volume(issue)/page/year: 37,1565,1984
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 2,87,1980
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 4,193,1973
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3535309

 Synonyms

Antibiotic yl-704 B3
Turimycin A3
Platenomycin-B3
Leucomycin V 3-acetate 4b-propanoate
Yl 704 B3
Leucomycin A6
Leukomycin A6