R 715

Modify Date: 2025-08-21 19:51:27

R 715 Structure
R 715 structure
Common Name R 715
CAS Number 185052-09-9 Molecular Weight 1140.33000
Density N/A Boiling Point N/A
Molecular Formula C57H81N13O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of R 715


R715 is a selective bradykinin B1 receptor antagonist. R715 significantly attenuates the hyperalgesic effect developed in Streptozotocin(HY-13753)-diabetic mice[1].

 Names

Name r 715

 R 715 Biological Activity

Description R715 is a selective bradykinin B1 receptor antagonist. R715 significantly attenuates the hyperalgesic effect developed in Streptozotocin(HY-13753)-diabetic mice[1].
Related Catalog
References

[1]. Gabra BH, et al. Beneficial effect of chronic treatment with the selective bradykinin B1 receptor antagonists, R-715 and R-954, in attenuating streptozotocin-diabetic thermal hyperalgesia in mice. Peptides. 2003;24(8):1131-1139.  

 Chemical & Physical Properties

Molecular Formula C57H81N13O12
Molecular Weight 1140.33000
Exact Mass 1139.61000
PSA 389.77000
LogP 3.67050
InChIKey DOSXOGUJJBDRGQ-VUBDHFCFSA-N
SMILES CCC(C)C(NC(=O)C(Cc1ccc2ccccc2c1)NC(=O)C(CO)NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)C1CCCN1C(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C(CCCCN)NC(C)=O)C(=O)O
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