(3S,4S)-PF-06459988 structure
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Common Name | (3S,4S)-PF-06459988 | ||
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CAS Number | 1858291-14-1 | Molecular Weight | 431.88 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C19H22ClN7O3 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of (3S,4S)-PF-06459988(3S, 4S)-PF-06459988 is the S enantiomer of PF-06459988 with less active. PF-06459988 is a potent irreversible inhibitor of T790M mutant epidermal growth factor receptor (EGFR). PF-06459988 has excellent selectivity against EGFR wild-type while possessing a minimally reactive electrophile that reduces the propensity of off-target labeling[1]. |
Name | (3S,4S)-PF-06459988 |
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Description | (3S, 4S)-PF-06459988 is the S enantiomer of PF-06459988 with less active. PF-06459988 is a potent irreversible inhibitor of T790M mutant epidermal growth factor receptor (EGFR). PF-06459988 has excellent selectivity against EGFR wild-type while possessing a minimally reactive electrophile that reduces the propensity of off-target labeling[1]. |
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Related Catalog | |
Target |
EGFR[1] |
References |
Molecular Formula | C19H22ClN7O3 |
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Molecular Weight | 431.88 |