YIR-819
Modify Date: 2024-09-23 12:21:37
YIR-819 structure
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Common Name | YIR-819 | ||
|---|---|---|---|---|
| CAS Number | 1883372-86-8 | Molecular Weight | 492.021 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H34ClN7O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of YIR-819YIR-819 is a small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 2.6 uM against YTA48P virus with no significant cytotoxicity (CC50=33 uM); A useful lead compound for the further development of HIV-1 entry inhibitors and could potentially be useful for co-administration with neutralizing antibodies for the treatment of HIV infection and AIDS. |
| Name | YIR-819 |
|---|
| Description | YIR-819 is a small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 2.6 uM against YTA48P virus with no significant cytotoxicity (CC50=33 uM); A useful lead compound for the further development of HIV-1 entry inhibitors and could potentially be useful for co-administration with neutralizing antibodies for the treatment of HIV infection and AIDS. |
|---|---|
| References | References 1. Ohashi N, et al. ChemMedChem. 2016 Apr 19;11(8):940-6. View Related Products by Target HIV |
| Molecular Formula | C23H34ClN7O3 |
|---|---|
| Molecular Weight | 492.021 |