Acetyl-Amyloid β-Protein (15-20) amide trifluoroacetate salt

Modify Date: 2024-01-02 20:05:49

Acetyl-Amyloid β-Protein (15-20) amide trifluoroacetate salt Structure
Acetyl-Amyloid β-Protein (15-20) amide trifluoroacetate salt structure
Common Name Acetyl-Amyloid β-Protein (15-20) amide trifluoroacetate salt
CAS Number 189064-06-0 Molecular Weight 822.99000
Density N/A Boiling Point N/A
Molecular Formula C42H62N8O9 Melting Point N/A
MSDS USA Flash Point N/A

 Use of Acetyl-Amyloid β-Protein (15-20) amide trifluoroacetate salt


Acetly-β Amyloid (15-20), Amide is a peptides fragment. Acetly-β Amyloid (15-20), Amide inhibits the β-sheet formation and stabilizes structure of Aβ (1–40) peptide. Acetly-β Amyloid (15-20), Amide can be used in study Alzheimer’s disease[1].

 Names

Name (2S)-2-acetamido-N-[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]pentanediamide
Synonym More Synonyms

  Biological Activity

Description Acetly-β Amyloid (15-20), Amide is a peptides fragment. Acetly-β Amyloid (15-20), Amide inhibits the β-sheet formation and stabilizes structure of Aβ (1–40) peptide. Acetly-β Amyloid (15-20), Amide can be used in study Alzheimer’s disease[1].
Related Catalog
References

[1]. Lin SY, et al. Fourier transform infrared spectroscopy used to evidence the prevention of beta-sheet formation of amyloid beta(1-40) peptide by a short amyloid fragment. Int J Biol Macromol. 2003 Sep;32(3-5):173-7.  

 Chemical & Physical Properties

Molecular Formula C42H62N8O9
Molecular Weight 822.99000
Exact Mass 822.46400
PSA 281.01000
LogP 4.32770

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles2

More Articles
Arrest of beta-amyloid fibril formation by a pentapeptide ligand.

J. Biol. Chem. 271 , 8545-8548, (1996)

Polymerization of amyloid beta-peptide (Abeta) into amyloid fibrils is a critical step in the pathogenesis of Alzheimer's disease. Here, we show that peptides incorporating a short Abeta fragment (KLV...

Controlling amyloid beta-peptide fibril formation with protease-stable ligands.

J. Biol. Chem. 272 , 12601-12605, (1997)

We have previously shown that short peptides incorporating the sequence KLVFF can bind to the approximately 40amino acid residue Alzheimer amyloid beta-peptide (Abeta) and disrupt amyloid fibril forma...

 Synonyms

Ac-QKLVFF-NH2,amyloid blocker
Ac-QKLVFF-NH2
amyloid blocker
Acetyl-Amyloid |A-Protein Fragment 15-20 Amide
Ac-QKLVFF