SuO-Glu-Val-Cit-PAB-MMAE

Modify Date: 2024-01-26 16:55:58

SuO-Glu-Val-Cit-PAB-MMAE Structure
SuO-Glu-Val-Cit-PAB-MMAE structure
Common Name SuO-Glu-Val-Cit-PAB-MMAE
CAS Number 1895916-24-1 Molecular Weight 1334.60
Density N/A Boiling Point N/A
Molecular Formula C67H103N11O17 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SuO-Glu-Val-Cit-PAB-MMAE


SuO-Glu-Val-Cit-PAB-MMAE consists a cleavable ADC linker (SuO-Glu-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE). SuO-Glu-Val-Cit-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name SuO-Glu-Val-Cit-PAB-MMAE

 SuO-Glu-Val-Cit-PAB-MMAE Biological Activity

Description SuO-Glu-Val-Cit-PAB-MMAE consists a cleavable ADC linker (SuO-Glu-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE). SuO-Glu-Val-Cit-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Auristatin

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

 Chemical & Physical Properties

Molecular Formula C67H103N11O17
Molecular Weight 1334.60