(R)-(-)-NIGULDIPINE HYDROCHLORIDE

Modify Date: 2024-01-24 05:13:51

(R)-(-)-NIGULDIPINE HYDROCHLORIDE structure	Common Name	(R)-(-)-NIGULDIPINE HYDROCHLORIDE
	CAS Number	189624-85-9	Molecular Weight	759.71700
	Density	N/A	Boiling Point	780.5ºC at 760 mmHg
	Molecular Formula	C₄₁H₄₄Cl₂N₄O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	425.8ºC

Name	5-O-ethenyl 3-O-methyl (2S)-2-[4-(4-benzhydrylpiperazin-1-yl)phenyl]-2,6-dimethyl-4-(3-nitrophenyl)-3,4-dihydro-1H-pyridine-3,5-dicarboxylate,dihydrochloride
Synonym	More Synonyms

Boiling Point	780.5ºC at 760 mmHg
Molecular Formula	C₄₁H₄₄Cl₂N₄O₆
Molecular Weight	759.71700
Flash Point	425.8ºC
Exact Mass	758.26400
PSA	116.93000
LogP	9.31740
Vapour Pressure	2.62E-24mmHg at 25°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: US7201200

CHEMICAL NAME :: 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-(4-(4- (diphenylmethyl)-1-piperazinyl)phenyl)ethyl methyl ester, dihydrochloride, (S)-(+)-

CAS REGISTRY NUMBER :: 189624-85-9

LAST UPDATED :: 199806

DATA ITEMS CITED :: 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: >12 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - conjunctive irritation Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 25(Suppl 3),S745,1997 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 14850 ug/kg/9D-I

TOXIC EFFECTS :: Liver - hepatitis (hepatocellular necrosis), diffuse Blood - normocytic anemia Related to Chronic Data - death

REFERENCE :: YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 25(Suppl 3),S793,1997

(S)-(+)-Watanidipine hydrochloride

BY 935

Watanidipine hydrochloride (S)-enantiomer

(S)-AE0047

(R)-Nigaldipine hydrochloride

3,5-Pyridinedicarboxylic acid,1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,2-(4-(4-(diphenylmethyl)-1-piperazinyl)phenyl)ethyl methyl ester,dihydrochloride,(S)-(+)

(-)-Nigaldipine hydrochloride

B 8509-035

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: (R)-(-)-NIGULDIPINE HYDROCHLORIDE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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(R)-(-)-NIGULDIPINE HYDROCHLORIDE

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Synonyms