Olacaftor
Modify Date: 2025-09-18 15:06:07
Olacaftor structure
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Common Name | Olacaftor | ||
|---|---|---|---|---|
| CAS Number | 1897384-89-2 | Molecular Weight | 539.661 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C29H34FN3O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of OlacaftorOlacaftor (VX-440, VX440) is a next-generation CFTR corrector, shows the potential to enhance the amount of CFTR protein at the cell’s surface and for treatment of cystic fibrosis. Fibrosis Phase 2 Clinical |
| Name | Olacaftor |
|---|---|
| Synonym | More Synonyms |
| Description | Olacaftor (VX-440, VX440) is a next-generation CFTR corrector, shows the potential to enhance the amount of CFTR protein at the cell’s surface and for treatment of cystic fibrosis. Fibrosis Phase 2 Clinical |
|---|---|
| References | References View Related Products by Target CFTR Fibrosis |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Molecular Formula | C29H34FN3O4S |
| Molecular Weight | 539.661 |
| Exact Mass | 539.225403 |
| LogP | 6.43 |
| Index of Refraction | 1.563 |
| InChIKey | NHOUNZMCSIHKHJ-FQEVSTJZSA-N |
| SMILES | CC(C)COc1cc(F)cc(-c2ccc(C(=O)NS(=O)(=O)c3ccccc3)c(N3CC(C)CC3(C)C)n2)c1 |
| Olacaftor |
| 6-(3-Fluoro-5-isobutoxyphenyl)-N-(phenylsulfonyl)-2-(2,2,4-trimethyl-1-pyrrolidinyl)nicotinamide |
| 3-Pyridinecarboxamide, 6-[3-fluoro-5-(2-methylpropoxy)phenyl]-N-(phenylsulfonyl)-2-(2,2,4-trimethyl-1-pyrrolidinyl)- |