7,8,9,10-tetrahydropyrimido[4,5-c]isoquinoline-1,3-diamine

Modify Date: 2026-08-23 17:52:21

7,8,9,10-tetrahydropyrimido[4,5-c]isoquinoline-1,3-diamine Structure
7,8,9,10-tetrahydropyrimido[4,5-c]isoquinoline-1,3-diamine structure
Common Name 7,8,9,10-tetrahydropyrimido[4,5-c]isoquinoline-1,3-diamine
CAS Number 19181-36-3 Molecular Weight 215.25400
Density 1.392g/cm3 Boiling Point 539.2ºC at 760 mmHg
Molecular Formula C11H13N5 Melting Point N/A
MSDS N/A Flash Point 313.6ºC

 Names

Name 7,8,9,10-tetrahydropyrimido[4,5-c]isoquinoline-1,3-diamine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.392g/cm3
Boiling Point 539.2ºC at 760 mmHg
Molecular Formula C11H13N5
Molecular Weight 215.25400
Flash Point 313.6ºC
Exact Mass 215.11700
PSA 92.17000
LogP 0.92820
Vapour Pressure 1.08E-11mmHg at 25°C
Index of Refraction 1.76
InChIKey JQMCAIXSFQXDFG-UHFFFAOYSA-N
SMILES Nc1nc(N)c2c3c(cnc2n1)CCCC3

 Synthetic Route

~%

7,8,9,10-tetrahydropyrimido[4,5-c]isoquinoline-1,3-diamine Structure

7,8,9,10-tetrah...

CAS#:19181-36-3

Learn More
Literature: Gangjee; Ohemeng; Lin; Katoh Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 2 p. 523 - 528

~40%

7,8,9,10-tetrahydropyrimido[4,5-c]isoquinoline-1,3-diamine Structure

7,8,9,10-tetrah...

CAS#:19181-36-3

Learn More
Literature: Gangjee; Ohemeng; Lin; Katoh Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 2 p. 523 - 528

~32%

7,8,9,10-tetrahydropyrimido[4,5-c]isoquinoline-1,3-diamine Structure

7,8,9,10-tetrah...

CAS#:19181-36-3

Learn More
Literature: Gangjee; Ohemeng; Lin; Katoh Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 2 p. 523 - 528

 Bioassay

View more

Name: ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania ...
Source: ChEMBL
Target: Glucose transporter
External Id: CHEMBL3436044
Name: Biochemical screen of P. falciparum CDPK1
Source: 1187
Target: Calcium-Dependent Protein Kinase 1 (CDPK1)
External Id: PfalCDPK1
Name: ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania ...
Source: ChEMBL
Target: Solute carrier family 2, facilitated glucose transporter member 1
External Id: CHEMBL3436042
Name: Biochemical screen of P. falciparum PK7
Source: 1187
Target: Protein Kinase 7 (PK7)
External Id: PfalPK7
Name: ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania ...
Source: ChEMBL
Target: Hexose transporter 1
External Id: CHEMBL3436043
Name: Biochemical screen of P. falciparum PK6
Source: 1187
Target: Protein Kinase 6 (PK6)
External Id: PfalPK6
Name: Biochemical screen of P. falciparum MAPK2
Source: 1187
Target: mitogen-activated protein kinase 2 (MAP2 or MAPK2)
External Id: PfalMAPK2
Name: Biochemical screen of P. falciparum CDPK4
Source: 1187
Target: Calcium-Dependent Protein Kinase 4 (CDPK4)
External Id: PfalCDPK4
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 Synonyms

1,3-Diamino-7,8,9,10-tetrahydropyrimido<4,5-c>isoquinoline
PY690
7,8,9,10-tetrahydro-pyrimido[4,5-c]isoquinoline-1,3-diamine
5,6-Tetramethylen-2,4-diamino-pyrido<2.3-d>-pyrimidin
Pyrimido[4,5-c]isoquinoline-1,3-diamine,7,8,9,10-tetrahydro
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