SA 16
Modify Date: 2024-09-22 19:42:23
SA 16 structure
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Common Name | SA 16 | ||
|---|---|---|---|---|
| CAS Number | 1919884-11-9 | Molecular Weight | 606.59 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C33H24F2N6O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SA 16A potent, dual PDK1 and Aurora kinase A inhibitor with IC50 of 416 and 35 nM, respectively; blocks glioblastoma multiforme (GBM) proliferation with no toxicity in normal cells, induces GBM apoptosis and inhibits cell migration; exhibits an increased efficacy against glioma stem cells (GSCs), inducing their differentiation and apoptosis. |
| Name | SA 16 |
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| Description | A potent, dual PDK1 and Aurora kinase A inhibitor with IC50 of 416 and 35 nM, respectively; blocks glioblastoma multiforme (GBM) proliferation with no toxicity in normal cells, induces GBM apoptosis and inhibits cell migration; exhibits an increased efficacy against glioma stem cells (GSCs), inducing their differentiation and apoptosis. |
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| References | References 1. Daniele S, et al. ACS Chem Neurosci. 2017 Jan 18;8(1):100-114. 2. Nagashima K, et al. J Biol Chem. 2011 Feb 25;286(8):6433-48. View Related Products by Target Aurora Kinase |
| Molecular Formula | C33H24F2N6O4 |
|---|---|
| Molecular Weight | 606.59 |