12-Hydroxymyricanone

Modify Date: 2024-02-04 19:38:13

12-Hydroxymyricanone Structure
12-Hydroxymyricanone structure
Common Name 12-Hydroxymyricanone
CAS Number 191999-68-5 Molecular Weight 372.412
Density 1.3±0.1 g/cm3 Boiling Point 628.1±55.0 °C at 760 mmHg
Molecular Formula C21H24O6 Melting Point N/A
MSDS N/A Flash Point 222.9±25.0 °C
Purity Quantity Budget Inquiry

 Use of 12-Hydroxymyricanone


12-Hydroxymyricanone is a nature product that could be isolated from the roots of Myrica nana. 12-Hydroxymyricanone inhibits the release of nitric oxide with an IC50 value of 30.19 μM[1].

 Names

Name 3,8,15-Trihydroxy-16,17-dimethoxytricyclo[12.3.1.12,6]nonadeca-1(18),2(19),3,5,14,16-hexaen-9-one
Synonym More Synonyms

 12-Hydroxymyricanone Biological Activity

Description 12-Hydroxymyricanone is a nature product that could be isolated from the roots of Myrica nana. 12-Hydroxymyricanone inhibits the release of nitric oxide with an IC50 value of 30.19 μM[1].
Related Catalog
In Vitro 12-Hydroxymyricanone (compound 8; 0-100 μM) 抑制 Lipopolysaccharides (HY-D1056) 激活的腹膜巨噬细胞中的一氧化氮释放[1]。
References

[1]. Wang J, et, al. Cyclic diarylheptanoids from Myrica nana inhibiting nitric oxide release. Bioorg Med Chem. 2008 Sep 15;16(18):8510-5.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 628.1±55.0 °C at 760 mmHg
Molecular Formula C21H24O6
Molecular Weight 372.412
Flash Point 222.9±25.0 °C
Exact Mass 372.157288
LogP 2.31
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.600

 Synonyms

Tricyclo[12.3.1.12,6]nonadeca-1(18),2,4,6(19),14,16-hexaen-9-one, 3,8,15-trihydroxy-16,17-dimethoxy-
3,8,15-Trihydroxy-16,17-dimethoxytricyclo[12.3.1.12,6]nonadeca-1(18),2(19),3,5,14,16-hexaen-9-one