2-(4-Amino-2-chlorophenyl)isoindoline-1,3-dione

Modify Date: 2025-09-10 18:45:08

2-(4-Amino-2-chlorophenyl)isoindoline-1,3-dione Structure
2-(4-Amino-2-chlorophenyl)isoindoline-1,3-dione structure
Common Name 2-(4-Amino-2-chlorophenyl)isoindoline-1,3-dione
CAS Number 19348-53-9 Molecular Weight 272.68600
Density 1.506g/cm3 Boiling Point 505.5ºC at 760 mmHg
Molecular Formula C14H9ClN2O2 Melting Point N/A
MSDS Chinese USA Flash Point 259.5ºC

 Names

Name N-(4-Amino-2-chlorophenyl)phthalimide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.506g/cm3
Boiling Point 505.5ºC at 760 mmHg
Molecular Formula C14H9ClN2O2
Molecular Weight 272.68600
Flash Point 259.5ºC
Exact Mass 272.03500
PSA 63.40000
LogP 3.36900
Vapour Pressure 2.42E-10mmHg at 25°C
Index of Refraction 1.716
InChIKey DRZDMSPFGPTPER-UHFFFAOYSA-N
SMILES Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2925190090

 Synthetic Route

~18%

2-(4-Amino-2-chlorophenyl)isoindoline-1,3-dione Structure

2-(4-Amino-2-ch...

CAS#:19348-53-9

Literature: Vamecq, Joseph; Bac, Pierre; Herrenknecht, Christine; Maurois, Pierre; Delcourt, Philippe; Stables, James P. Journal of Medicinal Chemistry, 2000 , vol. 43, # 7 p. 1311 - 1319

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2-(4-Amino-2-chlorophenyl)isoindoline-1,3-dione Structure

2-(4-Amino-2-ch...

CAS#:19348-53-9

Literature: Vamecq, Joseph; Bac, Pierre; Herrenknecht, Christine; Maurois, Pierre; Delcourt, Philippe; Stables, James P. Journal of Medicinal Chemistry, 2000 , vol. 43, # 7 p. 1311 - 1319

~%

2-(4-Amino-2-chlorophenyl)isoindoline-1,3-dione Structure

2-(4-Amino-2-ch...

CAS#:19348-53-9

Literature: Vamecq, Joseph; Bac, Pierre; Herrenknecht, Christine; Maurois, Pierre; Delcourt, Philippe; Stables, James P. Journal of Medicinal Chemistry, 2000 , vol. 43, # 7 p. 1311 - 1319

 Customs

HS Code 2925190090
Summary 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Bioassay

View more

Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay
Source: ChEMBL
Target: N/A
External Id: CHEMBL1266185
Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: Neurotoxicity by rotarod test after intraperitoneal administration at a concentration...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL733567
Name: Neurotoxicity determined by rotarod test after intraperitoneal administration at a co...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL728953
Name: Dicer-mediated maturation of pre-microRNA
Source: Center for Chemical Genomics, University of Michigan
Target: N/A
External Id: TargetID_659_CEMA
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
Name: MITF Measured in Cell-Based System Using Plate Reader - 2084-01_Activator_SinglePoint...
Source: Broad Institute
Target: N/A
External Id: 2084-01_Activator_SinglePoint_HTS_Activity
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 Synonyms

2-(4-amino-2-chlorophenyl)isoindole-1,3-dione
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