GW7604
Modify Date: 2025-09-14 00:03:18
GW7604 structure
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Common Name | GW7604 | ||
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| CAS Number | 195611-82-6 | Molecular Weight | 370.44 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H22O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GW7604GW7604 is an antiestrogen. GW7604 is the metabolite of GW5638, which is a high affinity estrogen receptor (ER) antagonist[1]. |
| Name | gw7604 |
|---|---|
| Synonym | More Synonyms |
| Description | GW7604 is an antiestrogen. GW7604 is the metabolite of GW5638, which is a high affinity estrogen receptor (ER) antagonist[1]. |
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| Related Catalog | |
| In Vitro | GW7604 is the presumed metabolite of GW5638 in breast (MCF-7) and endometrial (ECC-1) cell lines. GW7604 (0.1 nM-1 μM; 24 hours) inhibits both Estradiol (1 nM) and 4-hydroxytamoxifen (4-OHT; 10 and 100 nM) induction of TGF-alpha in a concentration related manner (1-1000 nM) in MDA-MB-231 cells[1]. Western Blot Analysis[1] Cell Line: MDA-MB-231 cells Concentration: 0.1 nM, 1 nM, 10 nM, 100 nM, 1 μM Incubation Time: 24 hours Result: Blocked the effect of estradiol (E2; 1 n M) in a concentration-related manner. |
| References |
| Molecular Formula | C25H22O3 |
|---|---|
| Molecular Weight | 370.44 |
| Exact Mass | 370.15700 |
| PSA | 57.53000 |
| LogP | 5.85910 |
| gw 7604 |