YKL-1-116
Modify Date: 2024-06-08 16:38:55
YKL-1-116 structure
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Common Name | YKL-1-116 | ||
|---|---|---|---|---|
| CAS Number | 1957202-71-9 | Molecular Weight | 606.731 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C34H38N8O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of YKL-1-116YKL-1-116 is a potent, selective and covalent inhibitor of CDK7 that does not inhibit other CDKs; synergizes with 5-FU or nutlin-3 to kill HCT116 cells, produces dose-dependent increases in PARP cleavage; is more potent than THZ1 towards both Cdk7WT and Cdk7as (analog-sensitive mutant). |
| Name | YKL-1-116 |
|---|
| Description | YKL-1-116 is a potent, selective and covalent inhibitor of CDK7 that does not inhibit other CDKs; synergizes with 5-FU or nutlin-3 to kill HCT116 cells, produces dose-dependent increases in PARP cleavage; is more potent than THZ1 towards both Cdk7WT and Cdk7as (analog-sensitive mutant). |
|---|---|
| References | References 1. Kalan S, et al. Cell Rep. 2017 Oct 10;21(2):467-481. View Related Products by Target Cyclin-dependent Kinase (CDK) |
| Molecular Formula | C34H38N8O3 |
|---|---|
| Molecular Weight | 606.731 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: YKL-1-116
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: YKL-1-116
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: YKL-1-116
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
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