8-Oxycoptisine

Modify Date: 2024-01-11 20:18:07

8-Oxycoptisine Structure
8-Oxycoptisine structure
Common Name 8-Oxycoptisine
CAS Number 19716-61-1 Molecular Weight 335.310
Density 1.6±0.0 g/cm3 Boiling Point 617.5±0.0 °C at 760 mmHg
Molecular Formula C19H13NO5 Melting Point N/A
MSDS N/A Flash Point 327.3±0.0 °C

 Use of 8-Oxycoptisine


8-Oxocoptisine is a natural protoberberine alkaloid with anti-cancer activity[1].

 Names

Name 6,7-Dihydro-4H-[1,3]dioxolo[4,5-g][1,3]dioxolo[7,8]isoquinolino[3,2-a]isoquinolin-4-one
Synonym More Synonyms

 8-Oxycoptisine Biological Activity

Description 8-Oxocoptisine is a natural protoberberine alkaloid with anti-cancer activity[1].
Related Catalog
In Vitro 8-Oxocoptisine has cytotoxicity against NCI-N87 (IC50=20.31 μM) and has no cytotoxicity against Caco-2 (IC50>100 μM)[1].
References

[1]. Ping Qian, et al. Five new alkaloids from Coptidis Rhizoma-Euodiae Fructus couple and their cytotoxic activities against gastrointestinal cancer cells. Fitoterapia. 2014 Mar;93:74-80.

 Chemical & Physical Properties

Density 1.6±0.0 g/cm3
Boiling Point 617.5±0.0 °C at 760 mmHg
Molecular Formula C19H13NO5
Molecular Weight 335.310
Flash Point 327.3±0.0 °C
Exact Mass 335.079010
LogP 4.65
Vapour Pressure 0.0±0.0 mmHg at 25°C
Index of Refraction 1.768
Storage condition 2-8℃

 Synonyms

6,7-Dihydro-4H-[1,3]dioxolo[4,5-g][1,3]dioxolo[7,8]isoquinolino[3,2-a]isoquinolin-4-one
4H-[1,3]Benzodioxolo[5,6-a]-1,3-benzodioxolo[4,5-g]quinolizin-4-one, 6,7-dihydro-
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