FR198248

Modify Date: 2024-02-01 12:10:28

FR198248 structure	Common Name	FR198248
	CAS Number	197316-54-4	Molecular Weight	198.17
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₉H₁₀O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of FR198248

FR198248 is an anti-influenza agent and peptide deformylase (PDF) inhibitor. FR198248 can be isolated from Aspergillus flavipes. FR198248 potently inhibits the PDF of Staphylococcus aureus with an IC50 of 3.6 µM. FR198248 can be used for antiviral and antibacterial research[1][2].

Name	2,3,4-trihydroxy-6-(hydroxymethyl)-5-methylbenzaldehyde
Synonym	More Synonyms

Description	FR198248 is an anti-influenza agent and peptide deformylase (PDF) inhibitor. FR198248 can be isolated from Aspergillus flavipes. FR198248 potently inhibits the PDF of Staphylococcus aureus with an IC50 of 3.6 µM. FR198248 can be used for antiviral and antibacterial research[1][2].
Related Catalog	Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection
Target	Influenza Virus, PDF[1][2].
References	[1]. Nishihara Y, et al. FR198248, a new anti-influenza agent isolated from Aspergillus terreus No. 13830 I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities. The journal of antibiotics, 2001, 54(2): 136-143. [2]. Kwon YJ, et al. Isolation and identification of FR198248, a hydroxylated 1,3-dihydroisobenzofuran, from Aspergillus flavipes as an inhibitor of peptide deformylase. Biosci Biotechnol Biochem. 2010;74(2):390-3.

Molecular Formula	C₉H₁₀O₅
Molecular Weight	198.17
Exact Mass	198.05300
PSA	97.99000
LogP	0.41660

1,5,6,7-Isobenzofurantetrol,1,3-dihydro-4-methyl

UNII-6ZL0C9ER7N

FR198248

Use of FR198248

Names

FR198248 Biological Activity

Chemical & Physical Properties

Synonyms