FR198248

Modify Date: 2024-02-01 12:10:28

FR198248 Structure
FR198248 structure
Common Name FR198248
CAS Number 197316-54-4 Molecular Weight 198.17
Density N/A Boiling Point N/A
Molecular Formula C9H10O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FR198248


FR198248 is an anti-influenza agent and peptide deformylase (PDF) inhibitor. FR198248 can be isolated from Aspergillus flavipes. FR198248 potently inhibits the PDF of Staphylococcus aureus with an IC50 of 3.6 µM. FR198248 can be used for antiviral and antibacterial research[1][2].

 Names

Name 2,3,4-trihydroxy-6-(hydroxymethyl)-5-methylbenzaldehyde
Synonym More Synonyms

 FR198248 Biological Activity

Description FR198248 is an anti-influenza agent and peptide deformylase (PDF) inhibitor. FR198248 can be isolated from Aspergillus flavipes. FR198248 potently inhibits the PDF of Staphylococcus aureus with an IC50 of 3.6 µM. FR198248 can be used for antiviral and antibacterial research[1][2].
Related Catalog
Target

Influenza Virus, PDF[1][2].

References

[1]. Nishihara Y, et al. FR198248, a new anti-influenza agent isolated from Aspergillus terreus No. 13830 I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities. The journal of antibiotics, 2001, 54(2): 136-143.

[2]. Kwon YJ, et al. Isolation and identification of FR198248, a hydroxylated 1,3-dihydroisobenzofuran, from Aspergillus flavipes as an inhibitor of peptide deformylase. Biosci Biotechnol Biochem. 2010;74(2):390-3.  

 Chemical & Physical Properties

Molecular Formula C9H10O5
Molecular Weight 198.17
Exact Mass 198.05300
PSA 97.99000
LogP 0.41660

 Synonyms

1,5,6,7-Isobenzofurantetrol,1,3-dihydro-4-methyl
UNII-6ZL0C9ER7N
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