(Z)-JIB-04 structure
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Common Name | (Z)-JIB-04 | ||
|---|---|---|---|---|
| CAS Number | 199596-24-2 | Molecular Weight | 308.765 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 472.9±55.0 °C at 760 mmHg | |
| Molecular Formula | C17H13ClN4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 239.8±31.5 °C | |
Use of (Z)-JIB-04(Z)-JIB-04 (NSC693627) is the Z isomer of JIB-04 that has two forms, E (HY-13953) and Z isomers. (Z)-JIB-04 is inactive in epigenetic analysis[1]. |
| Name | 5-Chloro-2-{(2Z)-2-[phenyl(2-pyridinyl)methylene]hydrazino}pyridine |
|---|---|
| Synonym | More Synonyms |
| Description | (Z)-JIB-04 (NSC693627) is the Z isomer of JIB-04 that has two forms, E (HY-13953) and Z isomers. (Z)-JIB-04 is inactive in epigenetic analysis[1]. |
|---|---|
| Related Catalog | |
| In Vitro | JIB-04 inhibits the demethylase activity of Jumonji enzymes in vitro and in cells, without affecting other α-ketoglutarate dependent hydroxylases or histone modifying enzymes [1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 472.9±55.0 °C at 760 mmHg |
| Molecular Formula | C17H13ClN4 |
| Molecular Weight | 308.765 |
| Flash Point | 239.8±31.5 °C |
| Exact Mass | 308.082886 |
| LogP | 3.92 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.644 |
| InChIKey | YHHFKWKMXWRVTJ-XLNRJJMWSA-N |
| SMILES | Clc1ccc(NN=C(c2ccccc2)c2ccccn2)nc1 |
| Storage condition | -20℃ |
|
Name: NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L...
Source: DTP/NCI
Target: N/A
External Id: MCF7_OneDose
|
|
Name: NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Non-Small Cell...
Source: DTP/NCI
Target: N/A
External Id: IGROV1_OneDose
|
| 5-Chloro-2-{(2Z)-2-[phenyl(2-pyridinyl)methylene]hydrazino}pyridine |
| Z-JIB-04 |
| NSC 693627 |
| JIB-04 (NSC 693627)-Z |