Paliperidone Palmitate
Paliperidone Palmitate structure
|
Common Name | Paliperidone Palmitate | ||
|---|---|---|---|---|
| CAS Number | 199739-10-1 | Molecular Weight | 664.893 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 736.3±70.0 °C at 760 mmHg | |
| Molecular Formula | C39H57FN4O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 399.1±35.7 °C | |
Use of Paliperidone PalmitatePaliperidone palmitate (9-Hydroxyrisperidone palmitate), an atypical long-acting antipsychotic agent, is an ester prodrug of Paliperidone. Paliperidone is a dopamine antagonist and 5-HT2A antagonist of the atypical antipsychotic class. Paliperidone palmitate shows efficacy against schizophrenia[1]. |
| Name | [3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-4-oxo-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-9-yl] hexadecanoate |
|---|---|
| Synonym | More Synonyms |
| Description | Paliperidone palmitate (9-Hydroxyrisperidone palmitate), an atypical long-acting antipsychotic agent, is an ester prodrug of Paliperidone. Paliperidone is a dopamine antagonist and 5-HT2A antagonist of the atypical antipsychotic class. Paliperidone palmitate shows efficacy against schizophrenia[1]. |
|---|---|
| Related Catalog | |
| Target |
5-HT2A Receptor D2 Receptor |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 736.3±70.0 °C at 760 mmHg |
| Molecular Formula | C39H57FN4O4 |
| Molecular Weight | 664.893 |
| Flash Point | 399.1±35.7 °C |
| Exact Mass | 664.436401 |
| PSA | 90.46000 |
| LogP | 9.85 |
| Vapour Pressure | 0.0±2.4 mmHg at 25°C |
| Index of Refraction | 1.590 |
| Storage condition | -20℃ |
|
~77%
Paliperidone Pa... CAS#:199739-10-1 |
| Literature: WO2012/164582 A1, ; Page/Page column 11-12 ; |
|
~90%
Paliperidone Pa... CAS#:199739-10-1 |
| Literature: WO2009/89076 A2, ; Page/Page column 15; 29 ; |
|
~81%
Paliperidone Pa... CAS#:199739-10-1 |
| Literature: WO2009/89076 A2, ; Page/Page column 28 ; |
|
~55%
Paliperidone Pa... CAS#:199739-10-1 |
| Literature: WO2009/89076 A2, ; Page/Page column 25-26 ; |
|
~10%
Paliperidone Pa... CAS#:199739-10-1 |
| Literature: WO2009/89076 A2, ; Page/Page column 9; 26 ; |
|
~%
Paliperidone Pa... CAS#:199739-10-1 |
| Literature: WO2012/164582 A1, ; |
|
~%
Paliperidone Pa... CAS#:199739-10-1 |
| Literature: WO2012/164582 A1, ; |
![3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one sodium structure](https://image.chemsrc.com/caspic/338/1172995-09-3.png)
![3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one structure](https://image.chemsrc.com/caspic/315/130049-82-0.png)
| 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido-[1,2-a]pyrimidin-4-one palmitate ester |
| 9-Hydroxyrisperidone palmitate |
| Xeplion |
| PALPERIDONE PALMITATE |
| UNII-R8P8USM8FR |
| Paliperidone Palmitate |
| Invega Sustenna |
| Paliperidone Palmitate [USAN] |
| 3-[2-[4-(6-fluoro-1,2-benzoisoxazol-3-yl)-1-piperidyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one palmitate ester |
| Hexadecanoic acid, 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl ester |
| 3-{2-[4-(6-Fluoro-1,2-benzoxazol-3-yl)-1-piperidinyl]ethyl}-2-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-9-yl palmitate |