3-AQC

Modify Date: 2025-09-18 10:24:04

3-AQC Structure
3-AQC structure
Common Name 3-AQC
CAS Number 201216-42-4 Molecular Weight 395.41200
Density N/A Boiling Point N/A
Molecular Formula C20H21N5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3-AQC


3-AQC, a piperazinylquinoxaline derivative, is a potent and competitive 5-HT3 receptor antagonist[1].

 Names

Name 3-(4-allylpiperazin-1-yl)-2-quinoxalinecarbonitrile maleate
Synonym More Synonyms

 3-AQC Biological Activity

Description 3-AQC, a piperazinylquinoxaline derivative, is a potent and competitive 5-HT3 receptor antagonist[1].
Related Catalog
Target

5-HT3 Receptor

In Vitro 3-AQC (化合物 7e) 的效力几乎比 Tropisetron (HY-B0072) 强 100 倍。在豚鼠回肠中对 2-methyl-5HT 的拮抗作用的 pA2 为10.2[1]。
References

[1]. A Monge, et al. Novel antagonists of 5-HT3 receptors. Synthesis and biological evaluation of piperazinylquinoxaline derivatives. J Med Chem. 1993 Sep 17;36(19):2745-50.  

 Chemical & Physical Properties

Molecular Formula C20H21N5O4
Molecular Weight 395.41200
Exact Mass 395.15900
PSA 130.65000
LogP 1.52418

 Synonyms

3-aqc
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here


Get all suppliers and price by the below link:

3-AQC suppliers

3-AQC price

Related Compounds: More...
3-(1-thiophen-3-ylpropyl)thiophene
141080-31-1
3-[(4-chloro-3-methyl-phenoxy)methyl]-5-(4-fluorophenyl)-4-(4-methylph enyl)-1,2,4-triazole
141079-08-5
3-CHLORO-4-(ISOPROPYLSULFONYL)THIOPHENE-2-CARBOXYLIC ACID
175202-26-3
3-[(4-chloro-3-methylphenoxy)methyl]-4,5-bis(4-methylphenyl)-1,2,4-triazole
141079-06-3
3-(4-chlorophenyl)-5-[(4-methylphenoxy)methyl]-4-(4-methylphenyl)-1,2,4-triazole
141079-01-8
3-[(4-methylphenoxy)methyl]-4,5-bis(4-methylphenyl)-1,2,4-triazole
141078-99-1
3-[4-(4-methylphenyl)-5-(phenoxymethyl)-1,2,4-triazol-3-yl]pyridine
141078-96-8
3,4-bis(4-methylphenyl)-5-(phenoxymethyl)-1,2,4-triazole
141078-91-3
3-phenyl-5,6-dihydro-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
141075-92-5
4-Methoxy-1-[1-(5-methylthiophene-2-carbonyl)azetidin-3-yl]piperidine
2034490-11-2
1-[3-(Quinoxalin-2-yloxy)pyrrolidin-1-yl]butan-1-one
2097893-84-8
2-Methoxy-1-[3-(quinoxalin-2-yloxy)pyrrolidin-1-yl]ethan-1-one
2097918-47-1
2-{[1-(4-Chlorobenzoyl)pyrrolidin-3-yl]oxy}quinoxaline
2097909-41-4
2-({1-[6-(Trifluoromethyl)pyridine-3-carbonyl]pyrrolidin-3-yl}oxy)quinoxaline
2097894-71-6
1-[3-(Quinoxalin-2-yloxy)pyrrolidin-1-yl]-2-(thiophen-3-yl)ethan-1-one
2097909-65-2
2-{[1-(2,3,4-Trifluorobenzoyl)pyrrolidin-3-yl]oxy}quinoxaline
2097928-41-9
N-[(4-chlorophenyl)methyl]-3-(quinoxalin-2-yloxy)pyrrolidine-1-carboxamide
2097904-32-8
N-[(4-fluorophenyl)methyl]-3-(quinoxalin-2-yloxy)pyrrolidine-1-carboxamide
2097916-80-6
1-Ethyl-4-[3-(quinoxalin-2-yloxy)pyrrolidine-1-carbonyl]piperazine-2,3-dione
2097916-87-3