3-AQC

Modify Date: 2024-01-11 16:12:42

3-AQC Structure
3-AQC structure
Common Name 3-AQC
CAS Number 201216-42-4 Molecular Weight 395.41200
Density N/A Boiling Point N/A
Molecular Formula C20H21N5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3-AQC


3-AQC, a piperazinylquinoxaline derivative, is a potent and competitive 5-HT3 receptor antagonist[1].

 Names

Name 3-(4-allylpiperazin-1-yl)-2-quinoxalinecarbonitrile maleate
Synonym More Synonyms

 3-AQC Biological Activity

Description 3-AQC, a piperazinylquinoxaline derivative, is a potent and competitive 5-HT3 receptor antagonist[1].
Related Catalog
Target

5-HT3 Receptor

In Vitro 3-AQC (化合物 7e) 的效力几乎比 Tropisetron (HY-B0072) 强 100 倍。在豚鼠回肠中对 2-methyl-5HT 的拮抗作用的 pA2 为10.2[1]。
References

[1]. A Monge, et al. Novel antagonists of 5-HT3 receptors. Synthesis and biological evaluation of piperazinylquinoxaline derivatives. J Med Chem. 1993 Sep 17;36(19):2745-50.  

 Chemical & Physical Properties

Molecular Formula C20H21N5O4
Molecular Weight 395.41200
Exact Mass 395.15900
PSA 130.65000
LogP 1.52418

 Synonyms

3-aqc
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