Fenitrothion-d6

Modify Date: 2024-01-12 16:08:34

Fenitrothion-d6 Structure
Fenitrothion-d6 structure
Common Name Fenitrothion-d6
CAS Number 203645-59-4 Molecular Weight 283.271
Density 1.4±0.1 g/cm3 Boiling Point 349.5±52.0 °C at 760 mmHg
Molecular Formula C9H6D6NO5PS Melting Point N/A
MSDS N/A Flash Point 165.2±30.7 °C

 Use of Fenitrothion-d6


Fenitrothion-d6 is the deuterium labeled Fenitrothion[1]. Fenitrothion, one of the most widely used organophosphorus pesticides, is a cholinesterase inhibiting insecticide/acaricid. Fenitrothion is widely used, as a broad-spectrum insecticide, on cotton crops, vegetables crops, fruit crops, and field crops especially paddy. Fenitrothion leads to accumulation of nitrophenols[2][3].

 Names

Name Fenitrothion-d6
Synonym More Synonyms

 Fenitrothion-d6 Biological Activity

Description Fenitrothion-d6 is the deuterium labeled Fenitrothion[1]. Fenitrothion, one of the most widely used organophosphorus pesticides, is a cholinesterase inhibiting insecticide/acaricid. Fenitrothion is widely used, as a broad-spectrum insecticide, on cotton crops, vegetables crops, fruit crops, and field crops especially paddy. Fenitrothion leads to accumulation of nitrophenols[2][3].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Abdel-Ghany R, et al. Impact of Exposure to Fenitrothion on Vital Organs in Rats. J Toxicol. 2016;2016:5609734.  

[3]. Qing Hong, et al. A microcosm study on bioremediation of fenitrothion-contaminated soil using Burkholderia sp. FDS-1. International Biodeterioration & Biodegradation

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 349.5±52.0 °C at 760 mmHg
Molecular Formula C9H6D6NO5PS
Molecular Weight 283.271
Flash Point 165.2±30.7 °C
Exact Mass 283.055054
PSA 115.41000
LogP 3.24
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.570

 Synonyms

O,O-Bis[(H)methyl] O-(3-methyl-4-nitrophenyl) phosphorothioate
(3-methyl-4-nitrophenoxy)-sulfanylidene-bis(trideuteriomethoxy)-λ<sup>5</sup>-phosphane
Phosphorothioic acid, O,O-dimethyl-d O-(3-methyl-4-nitrophenyl) ester