DL-Valine-d8

Modify Date: 2024-01-11 18:51:41

DL-Valine-d8 Structure
DL-Valine-d8 structure
Common Name DL-Valine-d8
CAS Number 203784-63-8 Molecular Weight 125.20
Density 1.136g/cm3 Boiling Point 213.6ºC at 760 mmHg
Molecular Formula C5H3D8NO2 Melting Point 295ºC (subl.)(lit.)
MSDS Chinese USA Flash Point 83ºC

 Use of DL-Valine-d8


DL-Valine-d8 is the deuterium labeled DL-Valine[1].

 Names

Name 2-amino-2,3,4,4,4-pentadeuterio-3-(trideuteriomethyl)butanoic acid
Synonym More Synonyms

 DL-Valine-d8 Biological Activity

Description DL-Valine-d8 is the deuterium labeled DL-Valine[1].
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Density 1.136g/cm3
Boiling Point 213.6ºC at 760 mmHg
Melting Point 295ºC (subl.)(lit.)
Molecular Formula C5H3D8NO2
Molecular Weight 125.20
Flash Point 83ºC
Exact Mass 125.12900
PSA 63.32000
LogP 0.75460
Vapour Pressure 0.0633mmHg at 25°C
Index of Refraction 1.461
Storage condition 2-8°C

 Safety Information

RIDADR NONH for all modes of transport

 Synonyms

DL-Valine-2,3,4,4,4,5,5,5-d8
MFCD00144194
DL-Valine-d8