3α,21-Dihydroxy-5α-pregnan-20-one-d3 structure
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Common Name | 3α,21-Dihydroxy-5α-pregnan-20-one-d3 | ||
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CAS Number | 203805-98-5 | Molecular Weight | 337.51 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C21H31D3O3 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of 3α,21-Dihydroxy-5α-pregnan-20-one-d33α,21-Dihydroxy-5α-pregnan-20-one-d3 (THDOC-d3) is the deuterium labeled 3α,21-Dihydroxy-5α-pregnan-20-one. 3α,21-Dihydroxy-5α-pregnan-20-one (THDOC), an endogenous neurosteroid, is a positive modulator of GABAA receptors. 3α,21-Dihydroxy-5α-pregnan-20-one potentiates neuronal response to low concentrations of GABA at α4β1δ GABAA receptors in vitro. |
Name | 3α,21-Dihydroxy-5α-pregnan-20-one-d3 |
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Description | 3α,21-Dihydroxy-5α-pregnan-20-one-d3 (THDOC-d3) is the deuterium labeled 3α,21-Dihydroxy-5α-pregnan-20-one. 3α,21-Dihydroxy-5α-pregnan-20-one (THDOC), an endogenous neurosteroid, is a positive modulator of GABAA receptors. 3α,21-Dihydroxy-5α-pregnan-20-one potentiates neuronal response to low concentrations of GABA at α4β1δ GABAA receptors in vitro. |
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Related Catalog | |
In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
References |
Molecular Formula | C21H31D3O3 |
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Molecular Weight | 337.51 |