CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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XZ4803000
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CHEMICAL NAME :
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1H-1,2,4-Triazole, 3,5-diphenyl-
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CAS REGISTRY NUMBER :
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2039-06-7
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LAST UPDATED :
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199712
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DATA ITEMS CITED :
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3
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MOLECULAR FORMULA :
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C14-H11-N3
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MOLECULAR WEIGHT :
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221.28
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WISWESSER LINE NOTATION :
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T5NN DNJ CR& ER
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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300 mg/kg
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TOXIC EFFECTS :
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Lungs, Thorax, or Respiration - respiratory depression
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REFERENCE :
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JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 50,597,1961
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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90 mg/kg
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TOXIC EFFECTS :
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Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
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REFERENCE :
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JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 50,597,1961 ** REPRODUCTIVE DATA **
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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DOSE :
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30 mg/kg
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SEX/DURATION :
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female 4-8 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
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REFERENCE :
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JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 26,1187,1983
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CAS#:64017-21-6