L-Asparagine-N-Fmoc,N-beta-trityl-15N2

Modify Date: 2024-01-09 10:33:32

L-Asparagine-N-Fmoc,N-beta-trityl-15N2 Structure
L-Asparagine-N-Fmoc,N-beta-trityl-15N2 structure
Common Name L-Asparagine-N-Fmoc,N-beta-trityl-15N2
CAS Number 204633-98-7 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of L-Asparagine-N-Fmoc,N-beta-trityl-15N2


L-Asparagine-N-Fmoc,N-beta-trityl-15N2 is a 15N-labeled Deruxtecan. Deruxtecan is an ADC drug-linker conjugate composed of a derivative of DX-8951 (DXd) and amaleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.

 Names

Name l-asparagine-n-fmoc, n-beta-trityl (15n2)

 L-Asparagine-N-Fmoc,N-beta-trityl-15N2 Biological Activity

Description L-Asparagine-N-Fmoc,N-beta-trityl-15N2 is a 15N-labeled Deruxtecan. Deruxtecan is an ADC drug-linker conjugate composed of a derivative of DX-8951 (DXd) and amaleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-240.

[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-240.

 Chemical & Physical Properties

No Any Chemical & Physical Properties