6-(3-Fluorophenyl)-6,7-dihydro-[1,3]dioxolo[4,5-G]quinolin-8(5H)-one

Modify Date: 2026-06-18 18:44:06

6-(3-Fluorophenyl)-6,7-dihydro-[1,3]dioxolo[4,5-G]quinolin-8(5H)-one Structure
6-(3-Fluorophenyl)-6,7-dihydro-[1,3]dioxolo[4,5-G]quinolin-8(5H)-one structure
Common Name 6-(3-Fluorophenyl)-6,7-dihydro-[1,3]dioxolo[4,5-G]quinolin-8(5H)-one
CAS Number 204841-46-3 Molecular Weight 285.27
Density N/A Boiling Point N/A
Molecular Formula C16H12FNO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 6-(3-Fluorophenyl)-6,7-dihydro-[1,3]dioxolo[4,5-G]quinolin-8(5H)-one

 Chemical & Physical Properties

Molecular Formula C16H12FNO3
Molecular Weight 285.27
InChIKey IJYJIPDFDHBJTD-UHFFFAOYSA-N
SMILES C1C(NC2=CC3=C(C=C2C1=O)OCO3)C4=CC(=CC=C4)F

 Bioassay

View more

Name: % inhibition of [3H]colchicine binding to bovine brain tubulin at a concentration of ...
Source: ChEMBL
Target: Tubulin beta-2B chain
External Id: CHEMBL817202
Name: Cytotoxicity against human breast cancer cells (MCF-7) using SRB assay.
Source: ChEMBL
Target: MCF7
External Id: CHEMBL707437
Name: Cytotoxicity against human epidermoid carcinoma of the nasopharyngeal cells (KB) usin...
Source: ChEMBL
Target: KB
External Id: CHEMBL705641
Name: Inhibition of bovine brain tubulin polymerization (ITP).
Source: ChEMBL
Target: Tubulin beta-2B chain
External Id: CHEMBL815874
Name: Cytotoxicity against human lung carcinoma cells (A-549) using SRB assay.
Source: ChEMBL
Target: A549
External Id: CHEMBL624706
Name: Cytotoxicity against human ileocecal carcinoma cells (HCT-8) using SRB assay.
Source: ChEMBL
Target: HCT-8
External Id: CHEMBL685740
Name: Cytotoxicity against human renal cancer cells (CAKI-1) using SRB assay.
Source: ChEMBL
Target: CAKI-1
External Id: CHEMBL651849
Name: The compound was tested for the cytotoxicity for the cell lines of human melanoma can...
Source: ChEMBL
Target: SK-MEL-2
External Id: CHEMBL805653
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