(S)-6-(3-Methoxyphenyl)-6,7-dihydro-[1,3]dioxolo[4,5-g]quinolin-8(5H)-one

Modify Date: 2026-04-27 18:16:21

(S)-6-(3-Methoxyphenyl)-6,7-dihydro-[1,3]dioxolo[4,5-g]quinolin-8(5H)-one Structure
(S)-6-(3-Methoxyphenyl)-6,7-dihydro-[1,3]dioxolo[4,5-g]quinolin-8(5H)-one structure
Common Name (S)-6-(3-Methoxyphenyl)-6,7-dihydro-[1,3]dioxolo[4,5-g]quinolin-8(5H)-one
CAS Number 204841-71-4 Molecular Weight 297.3
Density N/A Boiling Point N/A
Molecular Formula C17H15NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name (S)-6-(3-Methoxyphenyl)-6,7-dihydro-[1,3]dioxolo[4,5-g]quinolin-8(5H)-one

 Chemical & Physical Properties

Molecular Formula C17H15NO4
Molecular Weight 297.3
InChIKey IIXRKOHTDRHQQN-ZDUSSCGKSA-N
SMILES COC1=CC=CC(=C1)[C@@H]2CC(=O)C3=CC4=C(C=C3N2)OCO4

 Bioassay

View more

Name: % inhibition of [3H]colchicine binding to bovine brain tubulin at a concentration of ...
Source: ChEMBL
Target: Tubulin beta-2B chain
External Id: CHEMBL817202
Name: Cytotoxicity against human breast cancer cells (MCF-7) using SRB assay.
Source: ChEMBL
Target: MCF7
External Id: CHEMBL707437
Name: Cytotoxicity against human epidermoid carcinoma of the nasopharyngeal cells (KB) usin...
Source: ChEMBL
Target: KB
External Id: CHEMBL705641
Name: Inhibition of tubulin polymerization interacting at the colchicine binding site.
Source: ChEMBL
Target: Tubulin alpha-1A chain
External Id: CHEMBL817769
Name: Cytotoxicity against human lung carcinoma cells (A-549) using SRB assay.
Source: ChEMBL
Target: A549
External Id: CHEMBL624706
Name: Cytotoxicity against human ileocecal carcinoma cells (HCT-8) using SRB assay.
Source: ChEMBL
Target: HCT-8
External Id: CHEMBL685740
Name: Primary screen in NF54 nanoGlo assay, in single point, at 2uM, 72h
Source: ChEMBL
Target: Plasmodium falciparum
External Id: CHEMBL4888485
Name: Cytotoxicity against human renal cancer cells (CAKI-1) using SRB assay.
Source: ChEMBL
Target: CAKI-1
External Id: CHEMBL651849
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