(R)-6-(3-Methoxy-phenyl)-6,7-dihydro-5H-[1,3]dioxolo[4,5-g]quinolin-8-one

Modify Date: 2026-06-26 18:20:53

(R)-6-(3-Methoxy-phenyl)-6,7-dihydro-5H-[1,3]dioxolo[4,5-g]quinolin-8-one Structure
(R)-6-(3-Methoxy-phenyl)-6,7-dihydro-5H-[1,3]dioxolo[4,5-g]quinolin-8-one structure
Common Name (R)-6-(3-Methoxy-phenyl)-6,7-dihydro-5H-[1,3]dioxolo[4,5-g]quinolin-8-one
CAS Number 204841-72-5 Molecular Weight 297.3
Density N/A Boiling Point N/A
Molecular Formula C17H15NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name (R)-6-(3-Methoxy-phenyl)-6,7-dihydro-5H-[1,3]dioxolo[4,5-g]quinolin-8-one

 Chemical & Physical Properties

Molecular Formula C17H15NO4
Molecular Weight 297.3
InChIKey IIXRKOHTDRHQQN-CYBMUJFWSA-N
SMILES COC1=CC=CC(=C1)[C@H]2CC(=O)C3=CC4=C(C=C3N2)OCO4

 Bioassay

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Name: Cytotoxicity against human breast cancer cells (MCF-7) using SRB assay.
Source: ChEMBL
Target: MCF7
External Id: CHEMBL707437
Name: Cytotoxicity against human epidermoid carcinoma of the nasopharyngeal cells (KB) usin...
Source: ChEMBL
Target: KB
External Id: CHEMBL705641
Name: Inhibition of bovine brain tubulin polymerization (ITP).
Source: ChEMBL
Target: Tubulin beta-2B chain
External Id: CHEMBL815874
Name: Inhibition of tubulin polymerization interacting at the colchicine binding site.
Source: ChEMBL
Target: Tubulin alpha-1A chain
External Id: CHEMBL817769
Name: Cytotoxicity against human lung carcinoma cells (A-549) using SRB assay.
Source: ChEMBL
Target: A549
External Id: CHEMBL624706
Name: Cytotoxicity against human ileocecal carcinoma cells (HCT-8) using SRB assay.
Source: ChEMBL
Target: HCT-8
External Id: CHEMBL685740
Name: Cytotoxicity against human renal cancer cells (CAKI-1) using SRB assay.
Source: ChEMBL
Target: CAKI-1
External Id: CHEMBL651849
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