2'-MeCCPA

Modify Date: 2025-08-25 18:01:00

2'-MeCCPA Structure
2'-MeCCPA structure
 Common Name 2'-MeCCPA
CAS Number 205171-12-6 Molecular Weight 383.83000
Density 1.76g/cm3 Boiling Point 643.3ºC at 760 mmHg
Molecular Formula C16H22ClN5O4 Melting Point N/A
MSDS N/A Flash Point 342.9ºC

 Use of 2'-MeCCPA


2'-MeCCPA is a potent and selective A1 adenosine receptors (A1AR) agonist. 2'-MeCCPA efficiently inhibits cAMP modulation in both direct pathway medium spiny neurons (dMSNs) and indirect pathway medium spiny neurons (iMSNs)[1][2].

 Names

Name 2-[2-chloro-6-(cyclopentylamino)purin-9-yl]-5-(hydroxymethyl)-3-methyloxolane-3,4-diol
Synonym More Synonyms

 2'-MeCCPA Biological Activity

Description 2'-MeCCPA is a potent and selective A1 adenosine receptors (A1AR) agonist. 2'-MeCCPA efficiently inhibits cAMP modulation in both direct pathway medium spiny neurons (dMSNs) and indirect pathway medium spiny neurons (iMSNs)[1][2].
Related Catalog
Target

A1AR

In Vivo 2’-MeCCPA (1 nM-1 M) at reperfusion significantly reduces infarct size to risk ratio in male Sprague-Dawley rats[1].
References

[1]. J Bhandal, et al. Adenosine a1 receptor activation can protect the myocardium from ischaemia reperfusion injury post reperfusion. BMJ Journals. Volume 104, Issue Suppl 3.

[2]. Muntean BS, et al. Interrogating the Spatiotemporal Landscape of Neuromodulatory GPCR Signaling by Real-Time Imaging of cAMP in Intact Neurons and Circuits. Cell Rep. 2018 Jan 2;22(1):255-268.

 Chemical & Physical Properties

Density 1.76g/cm3
Boiling Point 643.3ºC at 760 mmHg
Molecular Formula C16H22ClN5O4
Molecular Weight 383.83000
Flash Point 342.9ºC
Exact Mass 383.13600
PSA 114.55000
LogP 1.17280
Vapour Pressure 1.98E-17mmHg at 25°C
Index of Refraction 1.777

 Synonyms

HMS3268H12
2'-IODO-2-PHENYLACETOPHENONE
2-chloro-2'-C-methyl-N6-cyclopentyl-adenosine
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Chemsrc provides 2'-MeCCPA(CAS#:205171-12-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of 2'-MeCCPA are included as well.>> amp version: 2'-MeCCPA

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