BTX161
Modify Date: 2025-10-10 08:06:41
BTX161 structure
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Common Name | BTX161 | ||
|---|---|---|---|---|
| CAS Number | 2052301-24-1 | Molecular Weight | 272.304 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C15H16N2O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BTX161BTX161 is a thalidomide analog that mediates degradation of CKIα better than lenalidomide in human AML cells and activates DDR and p53, while stabilizing the p53 antagonist MDM2; upregulates all the Wnt targets including MYC and does not affect MDM2 mRNA expression. |
| Name | BTX161 |
|---|
| Description | BTX161 is a thalidomide analog that mediates degradation of CKIα better than lenalidomide in human AML cells and activates DDR and p53, while stabilizing the p53 antagonist MDM2; upregulates all the Wnt targets including MYC and does not affect MDM2 mRNA expression. |
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| References | References 1. Minzel W, et al. Cell. 2018 Aug 20. pii: S0092-8674(18)30973-5. doi: 10.1016/j.cell.2018.07.045. View Related Products by Target Casein Kinase |
| Molecular Formula | C15H16N2O3 |
|---|---|
| Molecular Weight | 272.304 |