9-(3'-fluoro-3'-deoxyxylofuranosyl)adenine

Modify Date: 2024-01-22 13:18:26

9-(3'-fluoro-3'-deoxyxylofuranosyl)adenine Structure
9-(3'-fluoro-3'-deoxyxylofuranosyl)adenine structure
Common Name 9-(3'-fluoro-3'-deoxyxylofuranosyl)adenine
CAS Number 20535-16-4 Molecular Weight 269.23
Density N/A Boiling Point N/A
Molecular Formula C10H12FN5O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 9-(3'-fluoro-3'-deoxyxylofuranosyl)adenine


3’-Deoxy-3’-fluoro-xyloadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name (2R,3S,4S,5R)-5-(6-aminopurin-9-yl)-3-fluoro-2-(hydroxymethyl)oxolane-3,4-diol
Synonym More Synonyms

  Biological Activity

Description 3’-Deoxy-3’-fluoro-xyloadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C10H12FN5O3
Molecular Weight 269.23
Exact Mass 285.08700
PSA 139.54000

 Synonyms

9-Fdxa
9-(3'-Fluoro-3'-deoxyxylofuranosyl)adenine
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