Acid-PEG4-Sulfone-PEG4-acid

Modify Date: 2025-08-27 13:37:49

Acid-PEG4-Sulfone-PEG4-acid Structure
Acid-PEG4-Sulfone-PEG4-acid structure
Common Name Acid-PEG4-Sulfone-PEG4-acid
CAS Number 2055024-37-6 Molecular Weight 562.63
Density N/A Boiling Point N/A
Molecular Formula C22H42O14S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Acid-PEG4-Sulfone-PEG4-acid


Sulfone-Bis-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Sulfone-Bis-PEG4-acid

 Acid-PEG4-Sulfone-PEG4-acid Biological Activity

Description Sulfone-Bis-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C22H42O14S
Molecular Weight 562.63
InChIKey NABOCNYQXCVGJL-UHFFFAOYSA-N
SMILES O=C(O)CCOCCOCCOCCOCCS(=O)(=O)CCOCCOCCOCCOCCC(=O)O
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