M-Peg3-sulfone-peg3-t-butyl ester

Modify Date: 2024-01-11 08:36:52

M-Peg3-sulfone-peg3-t-butyl ester Structure
M-Peg3-sulfone-peg3-t-butyl ester structure
Common Name M-Peg3-sulfone-peg3-t-butyl ester
CAS Number 2055041-00-2 Molecular Weight 472.59
Density N/A Boiling Point N/A
Molecular Formula C20H40O10S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of M-Peg3-sulfone-peg3-t-butyl ester


m-PEG3-Sulfone-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name m-PEG3-Sulfone-PEG3-Boc
Synonym More Synonyms

 M-Peg3-sulfone-peg3-t-butyl ester Biological Activity

Description m-PEG3-Sulfone-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C20H40O10S
Molecular Weight 472.59

 Synonyms

MFCD29918256
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