Oxibendazole

Modify Date: 2024-01-02 15:26:51

Oxibendazole structure	Common Name	Oxibendazole
	CAS Number	20559-55-1	Molecular Weight	249.266
	Density	1.3±0.1 g/cm3	Boiling Point	459ºC
	Molecular Formula	C₁₂H₁₅N₃O₃	Melting Point	230-231°C
	MSDS	Chinese USA	Flash Point	N/A

Use of Oxibendazole

Oxibendazole is a broad-spectrum anthelmintic Target: AntiparasiticOxibendazole is a benzimidazole drug that is used to protect against roundworms, strongyles, threadworms, pinworms and lungworm infestations in horses and some domestic pets. It is usually white to yellowish in appearance, and may take the form of a powder or a tablet. From Wikipedia.

Name	Oxibendazole
Synonym	More Synonyms

Description	Oxibendazole is a broad-spectrum anthelmintic Target: AntiparasiticOxibendazole is a benzimidazole drug that is used to protect against roundworms, strongyles, threadworms, pinworms and lungworm infestations in horses and some domestic pets. It is usually white to yellowish in appearance, and may take the form of a powder or a tablet. From Wikipedia.
Related Catalog	Signaling Pathways >> Anti-infection >> Parasite Research Areas >> Infection
References	[1]. http://en.wikipedia.org/wiki/Oxibendazole

Density	1.3±0.1 g/cm3
Boiling Point	459ºC
Melting Point	230-231°C
Molecular Formula	C₁₂H₁₅N₃O₃
Molecular Weight	249.266
Exact Mass	249.111343
PSA	76.24000
LogP	2.50
Index of Refraction	1.635
Storage condition	2-8°C

Oxibendazole MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: FD0835000

CHEMICAL NAME :: Carbamic acid, (5-propoxy-1H-benzimidazol-2-yl)-, methyl ester

CAS REGISTRY NUMBER :: 20559-55-1

LAST UPDATED :: 199209

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C12-H15-N3-O3

MOLECULAR WEIGHT :: 249.30

WISWESSER LINE NOTATION :: T56 BM DNJ CMVO1 GO3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 32 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 30 mg/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 100 mg/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 300 mg/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - sex ratio

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 900 mg/kg

SEX/DURATION :: female 8-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 90 mg/kg

SEX/DURATION :: female 14-21 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - live birth index (measured after birth)

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Human Cells - not otherwise specified

DOSE/DURATION :: 2 mg/L

REFERENCE :: THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 31,505,1976

RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	FD0835000
HS Code	2933990090

N/A

CAS#:94526-10-0

Oxibendazole

CAS#:20559-55-1

Literature: Bulletin des Societes Chimiques Belges, , vol. 99, # 9 p. 673 - 701

N/A

CAS#:172362-95-7

Oxibendazole

CAS#:20559-55-1

Literature: Bulletin des Societes Chimiques Belges, , vol. 99, # 9 p. 673 - 701

5-propoxy-1,3-d...

CAS#:172362-91-3

Oxibendazole

CAS#:20559-55-1

Literature: Bulletin des Societes Chimiques Belges, , vol. 99, # 9 p. 673 - 701

Cyanamide

CAS#:420-04-2

4-Propoxy-1,2-d...

CAS#:56190-17-1

Methyl chloroformate

CAS#:79-22-1

~9%

Oxibendazole

CAS#:20559-55-1

Literature: Iddon, Brian Bulletin des Societes Chimiques Belges, 1990 , vol. 99, # 9 p. 673 - 701

Precursor 4
CAS#:172362-91-3 5-propoxy-1,3-d... CAS#:420-04-2 Cyanamide CAS#:56190-17-1 4-Propoxy-1,2-d... CAS#:79-22-1 Methyl chloroformate
DownStream 0

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Developing structure-activity relationships for the prediction of hepatotoxicity.

Chem. Res. Toxicol. 23 , 1215-22, (2010)

Drug-induced liver injury is a major issue of concern and has led to the withdrawal of a significant number of marketed drugs. An understanding of structure-activity relationships (SARs) of chemicals ...

A predictive ligand-based Bayesian model for human drug-induced liver injury.

Drug Metab. Dispos. 38 , 2302-8, (2010)

Drug-induced liver injury (DILI) is one of the most important reasons for drug development failure at both preapproval and postapproval stages. There has been increased interest in developing predicti...

Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): Identification of phenmedipham and amperozide as FAAH inhibitors

Bioorg. Med. Chem. Lett. 19 , 6793-6, (2009)

The screening of known medicinal agents against new biological targets has been shown to be a valuable approach for revealing new pharmacology of marketed compounds. Recently, carbamate, urea and keto...

Carbamic acid, N-(6-propoxy-1H-benzimidazol-2-yl)-, methyl ester

MFCD00801063

Oxibendazole

Oxbendazole

FENBENDAZOLE SULFOXIDE

Anthelcide EQ

Oxyibendazole

methyl 5-n-propoxybenzimidazole-2-carbamate

Anthdcide EQ

Methyl (5-propoxy-1H-benzimidazol-2-yl)carbamate

Oxbidazole

Equitac

Loditac

oxybendazole

obdz

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DC Chemicals Limited
China
Product Name: Oxibendazole
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Purity: 98.0%
Stocking Period: 3 Day
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Dayang Chem (Hangzhou) Co., Ltd.
China
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Purity: 98.0%
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Zhejiang Hangyu API Co., Ltd
China
Product Name: Oxibendazole
Price: ￥Inquiry/1kg
Purity: 99.5%
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: Oxibendazole
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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Oxibendazole

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