SL-651,498

Modify Date: 2025-08-21 12:17:58

SL-651,498 structure	Common Name	SL-651,498
	CAS Number	205881-86-3	Molecular Weight	389.42200
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₀FN₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SL-651,498

SL651498 is a full agonist of α2 and α3 GABAA receptors, and a partial agonist of α1 and α5 GABAA receptors. SL651498 shows anxiolytic and anticonvulsant activities[1].

Name	6-Fluoro-9-methyl-2-phenyl-4-(1-pyrrolidinylcarbonyl)-2,9-dihydro -1H-β-carbolin-1-one

Description	SL651498 is a full agonist of α2 and α3 GABAA receptors, and a partial agonist of α1 and α5 GABAA receptors. SL651498 shows anxiolytic and anticonvulsant activities[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor
References	[1]. G Griebel, et al. SL651498: an anxioselective compound with functional selectivity for alpha2- and alpha3-containing gamma-aminobutyric acid(A) (GABA(A)) receptors. J Pharmacol Exp Ther. 2001 Aug;298(2):753-68.

Molecular Formula	C₂₃H₂₀FN₃O₂
Molecular Weight	389.42200
Exact Mass	389.15400
PSA	47.24000
LogP	3.79540
InChIKey	QQWHWWDIFGNCLV-UHFFFAOYSA-N
SMILES	Cn1c2ccc(F)cc2c2c(C(=O)N3CCCC3)cn(-c3ccccc3)c(=O)c21

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Palmitic acid
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 6-FLUOR-2-FENYL-9-METHYL-4-(PYRROLIDINE-1-CARBONYL)-9H-PYRIDO[3,4B]INDOOL-1(2H)-ON
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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