T-Boc-aminooxy-peg4-ch2co2-t-bu

Modify Date: 2024-07-22 19:19:10

T-Boc-aminooxy-peg4-ch2co2-t-bu Structure
T-Boc-aminooxy-peg4-ch2co2-t-bu structure
Common Name T-Boc-aminooxy-peg4-ch2co2-t-bu
CAS Number 2062663-63-0 Molecular Weight 423.50
Density N/A Boiling Point N/A
Molecular Formula C19H37NO9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of T-Boc-aminooxy-peg4-ch2co2-t-bu


Boc-Aminooxy-PEG4-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Boc-Aminooxy-PEG4-CH2-Boc
Synonym More Synonyms

 T-Boc-aminooxy-peg4-ch2co2-t-bu Biological Activity

Description Boc-Aminooxy-PEG4-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Zhao B, et al. Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond. Pharmacol Rev. 2020 Apr;72(2):380-413.

 Chemical & Physical Properties

Molecular Formula C19H37NO9
Molecular Weight 423.50

 Synonyms

MFCD30536164