N-(Azido-PEG2)-N-Fluorescein-PEG3-acid

Modify Date: 2025-08-27 13:21:34

N-(Azido-PEG2)-N-Fluorescein-PEG3-acid Structure
N-(Azido-PEG2)-N-Fluorescein-PEG3-acid structure
Common Name N-(Azido-PEG2)-N-Fluorescein-PEG3-acid
CAS Number 2086689-04-3 Molecular Weight 767.80
Density N/A Boiling Point N/A
Molecular Formula C36H41N5O12S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-(Azido-PEG2)-N-Fluorescein-PEG3-acid


N-(Azido-PEG2)-N-Fluorescein-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-(Azido-PEG2)-N-Fluorescein-PEG3-acid

 N-(Azido-PEG2)-N-Fluorescein-PEG3-acid Biological Activity

Description N-(Azido-PEG2)-N-Fluorescein-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C36H41N5O12S
Molecular Weight 767.80
InChIKey PMJYXCRDKLEIKK-UHFFFAOYSA-N
SMILES [N-]=[N+]=NCCOCCOCCN(CCOCCOCCOCCC(=O)O)C(=S)Nc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21
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