Freselestat, (S)

Modify Date: 2025-08-27 22:18:40

Freselestat, (S) Structure
Freselestat, (S) structure
Common Name Freselestat, (S)
CAS Number 208847-91-0 Molecular Weight 452.5
Density N/A Boiling Point N/A
Molecular Formula C23H28N6O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name Freselestat, (S)

 Chemical & Physical Properties

Molecular Formula C23H28N6O4
Molecular Weight 452.5
InChIKey YSIHYROEMJSOAS-KRWDZBQOSA-N
SMILES CC(C)C(NC(=O)Cn1c(-c2ccccc2)ncc(N)c1=O)C(=O)c1nnc(C(C)(C)C)o1

 Freselestat, (S)Bioassay

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Name: Solubility was determined at a pH of 5.5 using physiological saline
Source: ChEMBL
Target: N/A
External Id: CHEMBL639376
Name: Solubility was determined at a pH of 7.4 using 1/14 M phosphate buffer
Source: ChEMBL
Target: N/A
External Id: CHEMBL639377
Name: Inhibition of HNE-induced lung hemorrhage in hamsters after oral administration of 30...
Source: ChEMBL
Target: Cricetinae gen. sp.
External Id: CHEMBL690252
Name: Binding constant derived from inhibition of elastase catalyzed hydrolysis of syntheti...
Source: ChEMBL
Target: Neutrophil elastase
External Id: CHEMBL677434
Name: Efficacy in po dosed hamster acute lung injury model
Source: ChEMBL
Target: Cricetinae
External Id: CHEMBL932243
Name: Inhibition of human neutrophil elastase
Source: ChEMBL
Target: Neutrophil elastase
External Id: CHEMBL932239
Name: Inhibition of HNE-induced lung hemorrhage in hamster after oral administration
Source: ChEMBL
Target: Neutrophil elastase
External Id: CHEMBL752067
Name: Inhibition of human neutrophil elastase HNE, hydrolysis of MeO-Suc-Ala-Ala-Pro-Val-pN...
Source: ChEMBL
Target: Neutrophil elastase
External Id: CHEMBL699807
Name: Solubility was determined at a pH of 1.2 using first fluid (JP13th)
Source: ChEMBL
Target: N/A
External Id: CHEMBL639374
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