Thalidomide-NH-(CH2)3-NH-Boc
Modify Date: 2025-08-27 11:32:04
Thalidomide-NH-(CH2)3-NH-Boc structure
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Common Name | Thalidomide-NH-(CH2)3-NH-Boc | ||
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| CAS Number | 2093386-36-6 | Molecular Weight | 430.45 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H26N4O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Thalidomide-NH-(CH2)3-NH-BocThalidomide-NH-(CH2)3-NH-Boc is a Boc-modified Thalidomide (HY-14658), which acts as a Cereblon ligand to recruit CRBN protein. The Boc protecting group at the end of Thalidomide-NH-(CH2)3-NH-Boc can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-NH-(CH2)3-NH-Boc is a key intermediate in the synthesis of CRBN-based designed PROTAC molecules targeting 11β-substituted estradiol. |
| Name | Thalidomide-NH-C3-NH-Boc |
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| Description | Thalidomide-NH-(CH2)3-NH-Boc is a Boc-modified Thalidomide (HY-14658), which acts as a Cereblon ligand to recruit CRBN protein. The Boc protecting group at the end of Thalidomide-NH-(CH2)3-NH-Boc can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-NH-(CH2)3-NH-Boc is a key intermediate in the synthesis of CRBN-based designed PROTAC molecules targeting 11β-substituted estradiol. |
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| Related Catalog |
| Molecular Formula | C21H26N4O6 |
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| Molecular Weight | 430.45 |