LCL 161, phenol

Modify Date: 2024-01-10 23:02:29

LCL 161, phenol Structure
LCL 161, phenol structure
Common Name LCL 161, phenol
CAS Number 2095244-42-9 Molecular Weight 598.75
Density N/A Boiling Point N/A
Molecular Formula C31H42N4O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LCL 161, phenol


E3 ligase Ligand 12 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 12 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].

 Names

Name E3 ligase Ligand 12

 LCL 161, phenol Biological Activity

Description E3 ligase Ligand 12 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 12 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
Related Catalog
References

[1]. Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.

 Chemical & Physical Properties

Molecular Formula C31H42N4O6S
Molecular Weight 598.75