CH7057288

Modify Date: 2025-08-25 09:21:34

CH7057288 Structure
CH7057288 structure
Common Name CH7057288
CAS Number 2095616-82-1 Molecular Weight 569.67
Density N/A Boiling Point N/A
Molecular Formula C32H31N3O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CH7057288


CH7057288 is a potent and selective TRK inhibitor.

 Names

Name CH7057288

 CH7057288 Biological Activity

Description CH7057288 is a potent and selective TRK inhibitor.
Related Catalog
Target

TRK

In Vitro CH7057288 induces regression of intracranial tumors and greatly improves event-free survival in an intracranial implantation model mimicking brain metastasis. CH7057288 can be a promising therapeutic agent for TRK fusion-positive cancer. TRK receptor tyrosine kinases are expressed as fusion proteins encoded by various fusion genes across a wide variety of cancer types, including lung and colorectal cancer[1].
References

[1]. Hiroshi Tanaka, et al. Abstract 4179: Potent and selective TRK inhibitor CH7057288. AACR Annual Meeting 2017; April 1-5, 2017.

 Chemical & Physical Properties

Molecular Formula C32H31N3O5S
Molecular Weight 569.67
Storage condition 2-8℃
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Price: ¥4386/10 mM * 1 mL in DMSO

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