LOXO-195 RS-isomer

Modify Date: 2024-09-25 21:41:09

LOXO-195 RS-isomer Structure
LOXO-195 RS-isomer structure
Common Name LOXO-195 RS-isomer
CAS Number 2097002-59-8 Molecular Weight 380.427
Density N/A Boiling Point N/A
Molecular Formula C20H21FN6O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LOXO-195 RS-isomer


The RS-isomer of LOXO-195, a potent, selective, next-generation Trk tyrosine kinase inhibitor with IC50 of 0.6 nM and <2.5 nM for WT TrkA and WT TrKC, respectively.

 Names

Name LOXO-195 RS-isomer

 LOXO-195 RS-isomer Biological Activity

Description The RS-isomer of LOXO-195, a potent, selective, next-generation Trk tyrosine kinase inhibitor with IC50 of 0.6 nM and <2.5 nM for WT TrkA and WT TrKC, respectively.
References References 1. Drilon A, et al. Cancer Discov. 2017 Sep;7(9):963-972. View Related Products by Target Trk Receptor

 Chemical & Physical Properties

Molecular Formula C20H21FN6O
Molecular Weight 380.427
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