Bis-PEG4-t-butyl ester

Modify Date: 2025-08-27 17:59:59

Bis-PEG4-t-butyl ester Structure
Bis-PEG4-t-butyl ester structure
Common Name Bis-PEG4-t-butyl ester
CAS Number 2100306-53-2 Molecular Weight 406.51
Density N/A Boiling Point N/A
Molecular Formula C20H38O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bis-PEG4-t-butyl ester


Bis-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bis-PEG4-t-butyl ester

 Bis-PEG4-t-butyl ester Biological Activity

Description Bis-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C20H38O8
Molecular Weight 406.51
InChIKey BEMRKFMWPQHBBR-UHFFFAOYSA-N
SMILES CC(C)(C)OC(=O)CCOCCOCCOCCOCCC(=O)OC(C)(C)C
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