S-Gboxin
Modify Date: 2025-08-24 23:21:12
S-Gboxin structure
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Common Name | S-Gboxin | ||
|---|---|---|---|---|
| CAS Number | 2101317-21-7 | Molecular Weight | 600.4647 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H32F3IN2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of S-GboxinS-Gboxin is an active analogue of Gboxin with potent antitumour activity. |
| Name | S-Gboxin |
|---|
| Description | S-Gboxin is an active analogue of Gboxin with potent antitumour activity. |
|---|---|
| In Vitro | S-Gboxin is an active analogue of Gboxin with potent antitumour activity. S-Gboxin inhibits growth of mouse and human glioblastoma (GBM) with an IC50 of 470 nM. Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma. Gboxin inhibits the growth of primary mouse and human glioblastoma cells but not that of mouse embryonic fibroblasts or neonatal astrocytes. Gboxin rapidly and irreversibly compromises oxygen consumption in glioblastoma cells. |
| Molecular Formula | C27H32F3IN2O2 |
|---|---|
| Molecular Weight | 600.4647 |
| InChIKey | DCAJNAWCJSUZDG-DZJKTSMVSA-M |
| SMILES | CC1CCC(C(C)C)C(OC(=O)Cn2c(-c3cccc(C(F)(F)F)c3)[n+](C)c3ccccc32)C1.[I-] |