S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate

Modify Date: 2026-08-14 14:46:54

S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate Structure
S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate structure
Common Name S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate
CAS Number 2127875-65-2 Molecular Weight 184.28
Density N/A Boiling Point N/A
Molecular Formula C5H12O3S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate


S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) and refers to the Alkyl-Chain composition. S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is the linker portions of the molecules employed for mAb attachment purposes[1].

 Names

Name S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate

  Biological Activity

Description S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) and refers to the Alkyl-Chain composition. S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is the linker portions of the molecules employed for mAb attachment purposes[1].
Related Catalog
Target

Cleavable

References

[1]. Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2019 Oct 31.

 Chemical & Physical Properties

Molecular Formula C5H12O3S2
Molecular Weight 184.28
Storage condition 2-8°C
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